Urea Plus 3% Metasense® Urea Plus 3% Cream, Metasense®

Urea Plus 3% Cream, Metasense®

75 g

A moisturizing and emollient cream for dry and sensitive skin. Suitable for daily use on all skin types.

Urea, Hyaluronic Acid, L-Arginine, Panthenol, Vitamin E

Helps increase skin hydration, reduce dryness, and improve skin softness.

Apply to clean, dry skin once or twice daily, or as directed by a physician. Massage gently until fully absorbed.

Pharmacology and Mechanism of Action Urea is a naturally occurring component of the skin and an essential constituent of the Natural Moisturizing Factor (NMF). It possesses hygroscopic properties, enabling it to attract and retain water within the stratum corneum. At a concentration of 3%, urea primarily acts as a humectant, helping to maintain skin hydration and prevent dryness.

Other ingredients in this product contribute to improved skin hydration and health through complementary mechanisms:

• Hyaluronic Acid: A powerful humectant that attracts and retains large amounts of water, helping to improve skin hydration and elasticity.
• L-Arginine: An amino acid that helps maintain skin hydration and supports the skin’s natural barrier function.
• Panthenol (Provitamin B5): Helps strengthen the skin barrier, improves skin softness, and reduces transepidermal water loss (TEWL) by increasing moisture retention in the stratum corneum.
• Vitamin E: A potent lipid-soluble antioxidant that helps protect the skin against oxidative stress and environmental aggressors, including UV-induced free radicals.

• For external use only. Do not apply to the eyes or mucous membranes.
• Do not use if you are allergic to urea or any of the other ingredients in this product.
• Do not apply to irritated skin, open wounds, or infected lesions.
• If redness, itching, or persistent irritation occurs, discontinue use and consult a physician if necessary.
• A mild burning or stinging sensation may occur upon initial application and is usually temporary. If it persists or worsens, discontinue use and consult a physician.

Store below 30°C, away from direct sunlight.